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Structures of USP7 in active and inactive states bound to DNMT1 revealed by cryo-EM
Structure
2025-07-19
Conformational plasticity of a BiP–GRP94 chaperone complex
Nature Structural & Molecular Biology
2025-07-15
A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics
Nature Structural & Molecular Biology
2025-07-20
Integrated machine learning and deep learning-based virtual screening framework identifies novel natural GSK-3β inhibitors for Alzheimer’s disease
Journal of Computer-Aided Molecular Design
2025-07-19
Molecular recognition and structural plasticity in amyloid–nucleic acid complexes
Journal of Structural Biology
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From droplets to diagnosis: AI-driven imaging and system integration in digital nucleic acid amplification testing
Biosensors & Bioelectronics
2025-07-19
APOE4-driven lipid metabolic dysregulation in Alzheimer's disease: Multi-pathway mechanisms and therapeutic perspectives
Biochemical and Biophysical Research Communications
2025-07-16
Phase separation via protein-protein and protein-RNA networks coordinates ribosome assembly in the nucleolus
Biochimica et Biophysica Acta-General Subjects
2025-07-18
E2F7 transcriptionally upregulates SPC24 to mediate aerobic Glycolysis and facilitate stemness of breast cancer
Journal of Bioenergetics and Biomembranes
2025-07-17
Neuronal VPS13D loss drives microglial activation
Nature Structural & Molecular Biology
2025-07-15
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