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Caged Glycan-Antibody Conjugates for Tumor-Selective Activation of Lysosome-Targeting Chimeras
Journal of Medicinal Chemistry
2026-08-15
Alzheimer’s Disease: A Review of Molecular Mechanisms and Interventions Targeting Aβ-Binding Receptors
ACS Chemical Neuroscience
2026-07-22
Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy
Journal of Medicinal Chemistry
2026-08-09
Unlocking the Dynamics of Human SPPL2a: First Atomistic Characterization of an Alzheimer’s-Linked Intramembrane Protease
Journal of Chemical Information and Modeling
2026-07-22
Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8
Journal of Medicinal Chemistry
2026-08-09
Design, Synthesis, and Evaluation of Novel Phenoselenazine Derivatives as Potent Modulators of Aβ42 Aggregation
Journal of Medicinal Chemistry
2026-07-29
Ginkgo biloba Leaf Extracts in Global Dementia and Mild Cognitive Impairment Guidelines. A Review
Planta Medica
2026-08-04
A Novel Dual-Targeting PROTAC Overcomes Endocrine Resistance by Engaging Orthosteric and Allosteric Sites of Estrogen Receptor α
Journal of Medicinal Chemistry
2026-08-09
Development of Aryl Cyano Amides for Fluorescence Discrimination of Tau and Amyloid Beta Deposits in Tissue
ACS Chemical Neuroscience
2026-07-22
Exploring the Therapeutic Potential of Chalcones in Alzheimer’s Disease: Mechanistic Insights and SAR Perspectives
Mini-Reviews in Medicinal Chemistry
2026-08-01
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